Israa G. Zainal; Mhammed AL-Dori; Abdul-Nasser M. Abdula
Abstract
The objective of this study was to determine the catalase activity (CAT),ceruloplasmin activity (CP), glutathione level (GSH) in the plasma of (44) normaldonars (22 male, 22 female,) ...
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The objective of this study was to determine the catalase activity (CAT),ceruloplasmin activity (CP), glutathione level (GSH) in the plasma of (44) normaldonars (22 male, 22 female,) and (66) patients with bladder cancer (22 smoker male, 22non smoker male, 22 female). Data analysis showed a significant decrease in the meanvalues of CAT (89.577 ± 17.140 of a smoker male, 92.102 ± 18.898 of non-smokermale, 90.225± 12.997 of a female) as compared to normal individuals (155.541 U/mgHb of a male, 150.797 U/mg Hb of a female) respectively, and GSH (0.109 ± 0.056 of asmoker male, 0.110 ± 0.051 of non-smoker male, 0.084 ± 0.028 of a female) ascompared to normal individuals (0.838 μmol/L of a male, 0.809 μmol/L of a female)respectively. A significant increase in the mean value of CP in plasma of patients withbladder cancer (56.477 ± 2.671 of a smoker male,55.602 ± 3.042 of non-smoker, 52.101± 3.212 of a female) was recorded as compared to normal individuals (43.908 IU of amale, 41.110 IU of a female) respectively, There is also a negative relationship betweenCAT & Cp and GSH & Cp levels (r = - 0.089, and r = - 0.104) respectively, while thereis a positive relationship between CAT and GSH (r = 0.081) in-patients with bladdercancer.
