Print ISSN: 1681-6900

Online ISSN: 2412-0758

Keywords : AMGA


Cytotoxic Effect of Vincarosea Aqueous Crude Extraction Human Brain Carcinoma Cell Line (AMGM) In Vitro

Liqaa H. Saqban; Hind H. Obaid; Dalia Azhar Ahmed; Dimah N. Passat; Mustafa N. J. Al-Darraji; Rafid M. Karim

Engineering and Technology Journal, 2016, Volume 34, Issue 3, Pages 129-140

The present study investigated the cytotoxic effects of aqueous crude extracts of Vincarosea leaves, flowers and seeds on Human brain carcinoma cell line (AMGA, Ahmed Majeed Glioblastoma Multiform ) in vitro, by using serial double dilution (concentration between 1.95-1000 µg/ml). The results showed that the cytotoxic effect of extracts was depended on type of parts of plant extracted, concentration and exposure time. The concentration 1000 µg/ml gave inhibition rate (IR), were (34, 49 and 64) % of leaves, flowers and seeds extracts respectively compared with control 100% after 24 hours from exposure time. However, low concentrations of aqueous extracts were found to induce the AMGA cells growth and proliferation (PR), it was 115% by treatment with aqueous extract offlowers extract in 1.95 µg/ml after 24 hours of exposed.