Print ISSN: 1681-6900

Online ISSN: 2412-0758

Keywords : cyclic citrullinated peptide

Estimation of Serum Anti-Cyclic CitrullinatedPeptide, Glutathione, Copper and Zinc in Patients with Multiple Sclerosis

Israa Zainal; Abdulnasser AL-Gebori

Engineering and Technology Journal, 2012, Volume 30, Issue 14, Pages 2461-2466

This study aimed to determine the level of anti-cyclic citrullinated peptide
(ACCP), glutathione (GSH), copper (Cu) and zinc (Zn) in sera of the patients with
Multiple Sclerosis (MS) and healthy subjects to examine their possible role in this
disease. Thirty patients in MS were included for evaluation of serum anti-cyclic
citrullinated peptide (ACCP), glutathione (GSH), copper (Cu) and zinc (Zn) and
they compared with thirty normal healthy subjects. Results revealed that the serum
levels of GSH and Cu were highly significant lower in MS patients than in healthy
control group p< 0.005. The mean serum levels of Zn for both groups were
significantly decrease p< 0.04, but the mean serum levels of ACCP in both groups
were no significantly decrease p > 0.201.