Print ISSN: 1681-6900

Online ISSN: 2412-0758

Keywords : SERS

Sensing Performance of Mono and Bimetallic Nano Photonics Surface Enhanced Raman Scattering (SERS) Devices

Doaa S. Jubair; Alwan M. Alwan; Walid K. Hamoudi

Engineering and Technology Journal, 2021, Volume 39, Issue 7, Pages 1174-1184
DOI: 10.30684/etj.v39i7.1982

In this research, sensing performance of mono and bimetallic nanophotonics SERS sensors of gold-silver nano-columns for the detection of chlorpyrifos was investigated. For optimum substrates for Gold-silver/nano-column surface-enhanced, Raman scattering (SERS) was achieved with the silicon substrate. By combining the Ag SERS activity with the Au chemical stability and nano-columns Si large field enhancement, the Au-Ag/nano-columns Si substrate revealed perfect reproducibility, homogeneity, sensitivity in addition to chemical stability. The sensors were tested by Atomic force microscope (AFM), field emission scanning electron microscope (FESEM), energy-dispersive X-ray analysis (EDS), and X-ray diffraction (XRD). Findings presented in this research indicated modified distributions and sizes of formed alloy nanoparticles, and the hot spots junctions within the nanophotonics layer after changing the nanoparticles types. The SERS sensors performance displayed an excellent recognition of ultra-low concentrations of chlorpyrifos solutions with an exponential relationship with the Raman signal. The highest enhancement factor (Ef=1.56×106) and minimum limit of detection 0.069 mg/Kg were obtained with Au-Ag sensors.

Synthesis and optimization of silver nanoparticles-antibody Herceptin conjugation for surface-enhanced Raman scattering (SERS)

Nasser Jaafer Zahid; Bejan Hashime; Mohamed Jafad Rasib; Afshin Mohtfir

Engineering and Technology Journal, 2015, Volume 33, Issue 9, Pages 1655-1662

We have developed surface-enhanced Raman spectroscopysubstratecomposed of antibody-conjugated silver nanoparticles as a functional nanoprobe. In this study, we synthesized silver nanoparticles with the pMBA linker for binding to antibody Herceptin and analyzed the binding of Herceptin to silver nanoparticles by Fourier Tranform Infrared (FT-IR). Our results clearly showed that a spherical shape of silver nanoparticles with a diameter of 50 µm has been performed. Furthermore, the obtained SERS probe apparently indicated that the intensity of antibody-conjugated silver nanoparticles as a SERS sensitive probe is increased by an enhancement factor of 105.