Honey is traditionally consumed as a nutrient, as well as for the enhancement of fertility. In this study, the effects of honey on reproductive hormones and histology of mice testis after 35 days of honey administrated orally. 18 adult male mice were divided into three groups: one control and two treated groups containing 6 mice in each group. Treated groups received honey in two different doses i.e 1.2 and 1.8 g/kg body weight, the results showed significant (P<0.05) increased in Testosterone, FSH and LH hormones between the three groups. Also there is significant increase in diameters of seminiferous tubules between control and the treated groups, while the results showed significant increased in primary spermatocytes and spermatids between 1.2 g/kg body weight treated group with other groups.