MgO nanoparticles were prepared by using sol-gel technique, the MgO nanoparticle was pure and chemically homogeneous, the determination of physio-chemical characterization of MgO nanoparticles showed standard techniques.
MgO nanoparticles were used in study their ability to inhibit the growth of E. coli, pseudomonas aeruginosa, S. aureus, Candida albicans were found that MIC was studied by MTT assay in presence of different MgO nanoparticles concentrations for 24 hour, the results showed that 40 μg/ml of MgO nanoparticles was effective for E.coli and pseudomonas aeruginosa, 20 μg/ml and S. aureus while Candida albicans inhibited with 30 μg/ml.
The shelf-life of MgO determined by agar plate methods MgO nanoparticles showed highly effective against selective pathogens by preventing the growth of gram positive and negative bacteria to more than 40 days and 21 days for fungi and this could significantly enhance microbial safety and extend the shelf-life of foods.