This study was amid to detect the active compounds in the aqueous extract of the plant Annona muricata
peel by chemical reagents and solutions. The results related that the aqueous extract of A. muricata
containing alkaloids, phenols, Flavanoids, terpenes, steroids, Saponins, glycosides. Thus, it could be
concluded that A. muricata should be considered as a promising medicinal plant, because of its contents of
active compounds, which are known by their medicinal properties, especially the antioxidant property. A.
muricata as antioxidant agents has been studies in different concentration (0.0, 10, 50, 100, 200, and 300)
μg/ml. Our result showed that ability of A. muricata extract to block H2O2 in destroys of DNA molecule.