Document Type : Research Paper
Author
Biomedical Engineering Department,University ofTechnology,
Abstract
This work take in consideration the application of Taguchi optimization methodology in optimizing the parameters for processing (composition, compounding pressure) and their effects on the output physical (Density and true porosity) properties and mechanical(fracture strength and microhardness) properties for the Nano HA,Al2O3 fillers reinforced HDPE hybrid composite material for orthodontic application. An orthogonal array of the Taguchi approach was used to analyses the effect of the processing parameters on the physical and mechanical properties. On the other hand, the surface roughness and particle size distribution were also calculated to study their effect on the output properties. The result shows that the Taguchi approach can determine the best combination of processing parameters that can provide the optimal physical and mechanical conditions, which are the optimum values (the optimum composition was15HA/ 5Al2O3/80HDPE, and optimum compounding pressure was102 MPa.
Keywords
Main Subjects
bone graft in orthopedic trauma,” J Bone Joint Surg Br, 82,
3-8, 2001.
[2] A.Chau, R. Mobbs “Bone graft substitutes in anterior
cervical discectomy and fusion,” Eur Spine J, 18, 449-64,
2009.
[3] K. Kaveh, R. Ibrahim, M. Bakar, T. Ibrahim, “Bone
grafting and bone graft substitutes,” J Anim Vet Adv, 9,
1055-67, 2010.
[4] R. Murugan, S.Ramakrishna “Bioactive nanomaterials
in bone grafting and tissue engineering,” In: Handbook of
nanostructured biomaterials and their applications in
nanobiotechnology, Nalwa HS (Ed.); American Scientific
Publishers: Stevenson Ranch USA, 2, 141-8, 2005.
[5] J. Tazaki, M.Murata, T. Yuasa, T. Akazawa, K. Ito, J.
Hino, “Autograft of human tooth and demineralized dentin
matrices for bone augmentation,” J Ceram Soc Jpn, 118,
442-5, 2010.
[6] J. Conway, “Autograft and nonunions: morbidity with
intramedullary bone graft versus iliac crest bone graft,”
Orthop Clin North Am, 41, 75-84, 2010.
[7] E. Keller, W.Triplett “Iliac crest bone grafting: review
of 160 consecutive cases,” J Oral Maxillofac Surg, 45, 11-
4, 1987.
[8] A.D. Thamir, J.S. Kashan, J.T.Alhaidary, “Effect of
Particle Size on the Physical and Mechanical Properties of
Nano HA/HDPE Bio-Composite for Synthetic Bone
Substitute,” Eng. & Tech. Journal, Vol. 32, Part (A), No.2,
2014.
[9] E. Tolba, B.M. Abd-Elhady, B. Elkholy, H. Elkady,
“Biomimetic Synthesis of Guided-Tissue Regeneration
Hydroxyapatite/Polyvinl Alcohol Nanocomposite
Scaffolds: Influence of Alignate on Mechanical and
Biological Properties,” J. Americ. Scie, 6,196, 2010.
[10] M. Wang, W. Bonfield, “Chemically coupled
hydroxyapatite- polyethylene composites: structure and
properties,” J. Biomater, 22, 1311, 2001.
[11] R.A. Sousa, R.L. Reis, A.M. Cunha, M.J. Bevies,
“Coupling of HDPE/hydroxyapatite Composite by Silanebased Methodologies,” J. Mater. Sci. Mater. In Medicine,
14, 475, 2003.
[12] R. L. Reis, A. M. Cunha, M.J. Oliveira, A.R.
Campos, M.J. Bevis, “Relationship between processing
and mechanical properties of injection molded high
molecular mass polyethylene + hydroxyapatite
composites,” J. Mat Res Innovat ,4, 263, 2001.
[13] S. Kangwantrakool, “Preparation of HydroxyapatitePolyethylene Biocomposites Using HA-nanoparticles by
Mechanically-Coating Method,” CMU Journal Special
Issue on Nanotechnology, 4, 95, 2005.
[14] M. Haneef, J. Rahman, M. Yunus, S. Zameer, S.
Patil, T. Yezdani, “Hybrid Polymer Matrix Composites
for Biomedical Applications,” IJMER, 3:2, pp-970-979,
2013.
[15] A. Tathe, M. Ghodke, A. Pratima, A. Nikalje, “Brief
review on biomaterials and their applications,”
International Journal of Pharmacy and Pharmaceutical
Sciences, Volume 2, Suppl 4 , pp 19-23, 2010.
[16] J. Black, G. Hasting “Handbook of biomaterials
Properties,” London, UK: Chapman Hall, 1998.
[17] E. Tolba, B.M. Abd-Elhady, B. Elkholy, H. Elkady,
“Biomimetic Synthesis of Guided-Tissue Regeneration
Hydroxyapatite/Polyvinl Alcohol Nanocomposite
Scaffolds, Influence of Alignate on Mechanical and
Biological Properties,” J. Americ. Scie, 6,196, 2010.
[18] AccuPyc 1330 Pycnometer Operator’s Manual V3.03,
Micromeritics Instrument Corporation, 2001.
[19] L. WANG, P. Henrique P. D’alipino, L.G. Lopes, J.C.
Perira, “Mechanical Properties of Dental Restorative
Materials: Relative Contribution of Laboratory tests, J.
Appl. Oral Sci, 11,162, 2003.
[20] A.T. Procopio, A. Zavaliangos, J.C. Cunningham
“Analysis of the diametrical compression test and the
applicability to plastically deforming materials,” J. Mater.
Sci., 38, 3629, 2003.
[21] www.malvern.com, Mastersizer Manual, Malvern
Instruments Limited Grovewood Road, Malvern,
Worcestershire, UK, WR14 1XZ.
[22] S.S. Mahapatra, A. Patnaik, “Study on mechanical and
erosion wear behavior of hybrid composites using Taguchi
experimental design,” Mater. Des. 30, 2791–2801, 2009.
[23] P. Ross, “Taguchi Techniques for Quality
Engineering: Loss Function, Orthogonal Experiments,
Parameter and Tolerance Design,” McGraw-Hill, New
York, 1998.
[24] T. Thamaraiselvi, S. Rajeswari, “Biological
Evaluation of Bioceramic Materials - A Review,” Trends
Biomater. Artif. Organs, 18, 1, pp 9-17, 2004.
[25] V. Sergey “Biocomposites and hybrid biomaterials
based on calcium orthophosphates,” Biomatter 1, 1, 3-56,
2011.
[26] T.Kokubo, H. Kim, M. Kawashita “Novel bioactive
materials with different mechanical properties,”
Biomaterials, 24, 2161-75, 2003.
[27] J.S. Kashan, A. Jha, A.D. Thamir, J.T. Al-Haidar, “A
kinetic analysis of the melting HA/Y-PSZ/HDPE nano
compositefor hard tissue materials,”Journal of King Saud
University – Engineering Sciences, 30, 286–29, 2018.
[28] J.S. Kashan, H. Jameel, “The Development of
Biomimetic Nano CaCO3/ PPBio Composites as Bone
Repair Materials-Optimal Thermal Properties Evaluation,”
J. of Babylon University/Engineering Sciences, No. 5,
Vol. 25, 1562-1571, 2017.
[29] J.S. Kashan, A.D.Thamir, J.T.Al-Haidary, “Effect of
Particle Size on the Physical and Mechanical Properties of
Nano HA/HDPE Bio-Composite for Synthetic Bone
Substitute,” Eng. & Tech. Journal, Vol.32, Part (A), No.2,
286-297, 2014.
)
