In this paper, the effect of CO2 laser on glaze-dental Zirconia ceramics after adding ZrO2 nanoparticles to glaze is introduced, and its improvement methods are studied. Specimens have been prepared using CAD/CAM dental machines and sintered at 1530o-C. Then the surface was glazed with VITA glaze plus (5% and 10%) Nano ZrO2. A 15W continuous CO2 laser was used as the indicator power to irradiate the glaze layer. The main phase of the ceramic substrate is tetragonal Zirconia, and the alumina content in the corundum phase is a certain percentage. The appearance of the varnish on the ceramic substrate changes the X-ray diffraction pattern through the appearance of new phases, which changes the crystallite size and the percentage of lattice strain. The range of grain size measured by atomic force microscopy was 88.46 nm to 62.18nm. In addition, the surface roughness was changed due to the appearance of crystal cores and grain growth. In addition, the addition of ZrO2 and laser irradiation changed the residual stress on the surface, which was reflected in the hardness value increased from 575 kg/mm2 to 1215 kg/mm2 after the laser treatment with the addition of 5% ZrO2. Generally, in terms of the structure and hardness of the surface of the glaze layer, the addition of 5% ZrO2 is better than 10%. SEM tests also showed no cracks in the central part of the treated area. These characteristics increase hardness.