The coordination between protective devices is the process of determining the most appropriate timing of power interruption during abnormal conditions in the power system. The aim of this work is to coordinate the protection of the 33/11 kV power distribution substation in Iraq using the CYME 7.1 software package. In this paper overcurrent and earth fault relays are simulated in two cases, with time delay setting and instantaneous setting, to obtain the Time Current Characteristics (TCC) curves for each Circuit Breaker (CB) relay of Al-Karama substation (2×31.5 MVA, 33/11 kV) in Babil distribution network. The short circuit current at each CB is calculated and accordingly, the protection coordination for Al-Karama substation has been simulated. The TCC curves have been obtained in two cases for overcurrent and earth fault relays; in a case with time delay setting and in the case with the instantaneous setting. The setting takes into consideration the short circuit current at the furthest point of the longest outgoing feeder and the shortest outgoing feeder.