2-(2-imino-1-methylimidazolidin-4-ylidene)hydrazinecarbothioamide react
with chlorides of Cr(III), Co(II), Ni(II) and Cu(II) to yield metal ion complexes of
definite composition. These compounds were characterized by elemental analyses,
magnetic susceptibility measurements, UV-visible, 1H-NMR and FT-IR spectral
investigations. The ligand was studied by using of theoretical method (Simi
empirical AMI module in the CS ChemOffice molecular modeling package) by
calculation of heat of formation, bond length, bond angle and dihedral angle. The
stability for the prepared complexes was studied theoretically by the Density
Function Theory (DFT). The free ligand and their metal complexes have been
tested in vitro against a number of micro-organisms (Staphylococcus aureus, E.
coli, Proteus vulgaris, Pseudomonas, and Klebsiella pneumoniae), in order to
assess their antimicrobial activities. The ligand and its complexes showed
considerable activity against all bacteria.