The Cytotoxicity Effect of Ethanolic Crude Extract of Petroselinum Crispum on Cancer Cell Line Hela
Engineering and Technology Journal,
2011, Volume 29, Issue 12, Pages 507-517
AbstractThis study amid to investigate the effects of ethanolic crude extract of Petroselium cripum leaves on the proliferation of the cancer cell line HeLa .
The cytotoxicity of cancer cell line of concentration of (0.95, 1.9,3.8,7.7,15.5,31.25,62.5,125,250,500,1000,2000,3000,4000,6000,8000, 10000, 12000 and 16000)μg/ml showed there was no inhibition observed at concentration (o.95,1.9,3.8,7.7,15.5,31.25and 62.5)μg/ml. While at concentration of 250,500 and 1000 mg/ml the inhibition percentage was less than 50%.But at concentration of 2000 and 4000μg/ml the inhibition percentage was(63%,66%) respectively at while after 48hrs the concentration of (6000,8000,10000,12000,14000 and16000)μg/ml the inhibition percentage was more than70% this study was found that the alcoholic extract hase toxic effect on cancer cell line ,on the inhibition percentage of HeLa cell line was 73.840% and 79.238% at concentration of 6000μg/ml and 16000 μg/ml after 24hrs the percentage79.930% at concentration 6000 μg/ml to 86.505% at concentration16000 μg/ml after 48hrs. exposure and the percentage was 82.353% at concentration 6000 μg/ml to 88.581% at concentration16000 μg/ml after 72hrs .From this result we can conclude that this plant have a promising medical plant effect on cancer,through out the toxic effects on cancer cell line .
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