The study enrolled a total of 33 patients with congestive heart failure,
angina pectoris and myocardial infarction for evaluation of the activity of enzymes, creatine kinase, and aspartate transaminase, concentrations of calcium, cholesterol, and triglyceride and they were compared with 16 normal healthy human. .This study involved three groups of patients a first one consisted of 9 patients with congestive heart failure. Second group of 9 patients with angina pectoris with chest pain. Third group consisted of 15 patients with myocardial infarction. They were obtained from Ibn-Al-Bay tar hospital and Ibn-Al-Nafess for cardiac care unit of Baghdad. They were investigated for enzymes activity and concentration of calcium, cholesterol,
and triglyceride. There was very highly significant increase in the activities of creatine kinase, aspartate transaminase (P< 0.001) with different heart diseases when compared with normal healthy subjects. The result demonstrated a statistically significant decrease in the concentration of calcium (P< 0.001) and significant increase in concentration of Cholesterol and triglyceride when compared with normal healthy subjects with different heart diseases (P< 0.001).