Authors
Abstract
The aim of this research is to compare the electrochemical behavior of two surgical implant biomaterials alloys, SS 316L and Co–Cr–Mo alloy in simulated body fluid. This comparison is focused on the influence of presence of three anti-inflammatory drugs, aspirin (C9H8O4), paracetamol (C8H9NO2), and mefenamic acid (C15H15NO2) with three
concentrations of each drug (0.00303, 0.00606, and 0.01212), (0.0086, 0.0172, and 0.0344), and (0.00111, 0.00156, and 0.00201) g/300ml respectively at pH=7.4 and 37oC using electrochemical techniques, potentiodynamic curves and potentiostatic tests. Influence of these drugs on both biomaterials depends on the formation of
organometallic complexes between released metals ions from implant alloys and drugs molecules. The study shows that the drugs behave as inhibitors for SS 316L through the measured corrosion parameters, while gives irregular behavior in the case of Co – Cr – Mo alloy. However, difference between two alloys appear with different affinity of
released metal ions to binding with other molecules inside human body.
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