Malava is an important medicinal plant used as a remedy for cut wound, eczema, dermal infected wounds, bronchitis, and digestive problems. To evaluate the scientific basis for the use of the plant, the antimicrobial activity of different concentrations of aqueous and ethanolic malva leaves extract were investigated in vitro against five pathogenic bacteria (Proteus sp, Salmonell sp, Kliebsiella pneumoniae,Pseudomonas aeruginosa and Staphylococcus aereus) The results indicated that all concentrations showed an antimicrobial activity against all the tested bacteria, the highest activities were against S.aureus,with the inhibition zone was (25 )mm ,(20)mm at (0.1)% ethanolic and aqueous con respectively .The biological activity of ethanolic and aqueous extract of malva leaves when compared with some antibiotic include: Tetracycline, Gentamycin, Ampicillin, Carbinicilin and Erythromycin. Antimicrobial of the lowest conc(0.01%) of malva leaves was better than all antibiotics against all tested pathogenic bacteria.